GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs35432774 | chr7:65393019 | CCT6P1 | chr7:65216092-65228661:+ | 0.67 | 4.9 | 3.88E-6 | Diabetic kidney disease |
| THYM | cis | rs9894429 | 1 | rs35435780 | chr17:79579602 | TSPAN10 | chr17:79609349-79615778:+ | 0.63 | 6.68 | 1.61E-9 | Eye color traits |
| THYM | cis | rs6932590 | 1 | rs35454259 | chr6:27254475 | LOC100270746 | chr6:26987146-26988085:- | 0.48 | 4.64 | 1.13E-5 | Schizophrenia |
| THYM | cis | rs911119 | 1 | rs35488434 | chr20:23620401 | CST9 | chr20:23583049-23586610:- | -0.48 | -4.46 | 2.25E-5 | Chronic kidney disease |
| THYM | cis | rs2066819 | 1 | rs35526714 | chr12:56634639 | RPS26 | chr12:56435686-56438005:+ | -0.94 | -4.54 | 1.66E-5 | Psoriasis vulgaris |
| THYM | cis | rs2243480 | 1 | rs35542501 | chr7:65431215 | CCT6P1 | chr7:65216092-65228661:+ | 0.62 | 5.1 | 1.73E-6 | Diabetic kidney disease |
| THYM | cis | rs2028299 | 1 | rs35608327 | chr15:90369204 | AP3S2 | chr15:90373832-90456222:- | -0.42 | -4.66 | 1.02E-5 | Type 2 diabetes |
| THYM | cis | rs12780845 | 1 | rs35630951 | chr10:17215649 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.72 | 8.18E-6 | Homocysteine levels |
| THYM | cis | rs1559040 | 1 | rs35641543 | chr2:54347313 | RTN4 | chr2:55199329-55277734:- | -0.5 | -4.14 | 7.39E-5 | Sudden cardiac arrest |
| THYM | cis | rs4663866 | 1 | rs35648651 | chr2:239133843 | LOC151174 | chr2:239133754-239140318:- | 0.94 | 4.73 | 7.74E-6 | Irritable bowel syndrome |
| THYM | cis | rs10935120 | 1 | rs35718987 | chr3:134272783 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs35718987 | chr3:134272783 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs13073838 | 1 | rs35723648 | chr3:74627121 | CNTN3 | chr3:74311722-74570343:- | 0.47 | 4.8 | 5.86E-6 | Economic and political preferences |
| THYM | cis | rs2243480 | 1 | rs35735127 | chr7:65300423 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 4.78 | 6.3E-6 | Diabetic kidney disease |
| THYM | cis | rs2120019 | 1 | rs35736167 | chr15:75332002 | PPCDC | chr15:75315927-75343066:+ | 0.27 | 4.85 | 4.8E-6 | Blood trace element (Zn levels) |